Synthesis of L-[4,4-2H2] and D,L-[3,3,4,4-2H4] methionine

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Comparative metabolism of L-methionine, DL-methionine and DL-2-hydroxy 4-methylthiobutanoic acid by broiler chicks.

1. Metabolism, in broiler chicks, of DL-2-hydroxy 4-methylthiobutanoic acid (DL-HMB), DL-methionine and L-methionine was compared in vivo using 14C-labelled tracers. 2. The distribution of L-[1-14C]methionine and DL-[1-14C]HMB in the major body tissues was examined for a period of 120 min after administration. 3. The relative oxidation (14CO2 exhaled), excretion and incorporation into tissue pr...

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Efficacy of DL-methionine hydroxy analog free acid and DL-methionine as methionine sources for pigs.

Two experiments were conducted to evaluate the efficacy of dietary DL-methionine hydroxy analog-free acid (MHA-FA, 88%) compared with DL-methionine (DLM, 99%) as Met sources in pigs. In Exp. 1, a total of 245 crossbred pigs (initial BW of 6.4 kg [SD = 0.5]) were allotted to 7 treatments in 7 replicates for an experimental period of 28 d. The basal diet (BD) was formulated to contain 17.5% CP an...

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Preparation of d- and l-methionine from dl-methionine by enzymatic resolution.

It has been shown previously (1,2) that the synthesis of CO-NH linkages by papain as well as by other proteinases is characterized by extreme stereochemical specificity. Thus, upon the addition of cysteine-activated papain to a mixture of carbobenzoxy-nn-glutamic acid and aniline, there is formed carbobenzoxy-L-glutamic acid anilide, which separates in crystalline form. The carbobenzoxy-n-gluta...

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Effect of fasting and of methionine deficiency on L-methionine, DL-methionine and DL-2-hydroxy-4-methylthiobutanoic acid metabolism in broiler chicks.

Metabolism of L-[1-14C]methionine, DL-[1-14C]methionine and DL-[1-14C]2-hydroxy-4-methylthiobutanoic acid (DL-HMB) by broiler chicks which had been fasted overnight or given a methionine-deficient diet was compared with fed (control) birds. The excretion of 14C-labelled material, total 14CO2 exhaled, 14C incorporation into tissue proteins and the 14C-labelled material in perchloric-acid-soluble...

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Bioavailability comparison between herbal methionine and DL-methionine on growth performance and immunocompetence basis in broiler chickens

BACKGROUND:Herbal methionine can be compared relative toDl-methionine with evaluation of bioavailability of this source ofmethionine. OBJECTIVES: An experiment was carried out todetermine the relative bioefficacy of herbal methionine (H-Met)®relative to DL-methionine (DL-Met) on performance criteria andimmunocompetence of Met sources in male broilers. Atotal of 160male broilers were fed a Met-d...

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ژورنال

عنوان ژورنال: Journal of Labelled Compounds and Radiopharmaceuticals

سال: 1984

ISSN: 0362-4803

DOI: 10.1002/jlcr.2580210609